{"id":57321,"date":"2020-11-23T20:15:59","date_gmt":"2020-11-23T20:15:59","guid":{"rendered":"https:\/\/www.zinpro.com\/improve-epithelial-tissue-function-to-prevent-bacterial-chondronecrosis-and-osteomyelitis-in-poultry-production\/"},"modified":"2023-07-19T13:10:20","modified_gmt":"2023-07-19T18:10:20","slug":"improve-epithelial-tissue-function-to-prevent-bacterial-chondronecrosis-and-osteomyelitis-in-poultry-production","status":"publish","type":"post","link":"https:\/\/www.zinpro.com\/pt\/resource-center\/blog\/improve-epithelial-tissue-function-to-prevent-bacterial-chondronecrosis-and-osteomyelitis-in-poultry-production\/","title":{"rendered":"Melhorar a fun\u00e7\u00e3o do tecido epitelial para inibir a condronecrose bacteriana e a osteomielite na produ\u00e7\u00e3o av\u00edcola"},"content":{"rendered":"

Esta \u00e9 a terceira parte de uma s\u00e9rie de quatro partes sobre o fortalecimento do tecido epitelial em aves. Outros artigos desta s\u00e9rie incluem Fortale\u00e7a a fun\u00e7\u00e3o do tecido epitelial na produ\u00e7\u00e3o av\u00edcola com suplementos de minerais tra\u00e7os de desempenho<\/a>, Melhorar a fun\u00e7\u00e3o do tecido epitelial para inibir a condronecrose bacteriana e a osteomielite na produ\u00e7\u00e3o av\u00edcola<\/a>e How to Maintain Proper Epithelial Tissue Function to Ensure Poultry Food Safety (Como manter a fun\u00e7\u00e3o adequada do tecido epitelial para garantir a seguran\u00e7a dos alimentos para aves).<\/a><\/p>\n\n\n\n

Tecido epitelial fraco pode causar BCO e outras doen\u00e7as em aves<\/h2>\n\n\n\n

Quando o tecido epitelial de uma ave est\u00e1 enfraquecido, bact\u00e9rias e outros ant\u00edgenos podem passar para o corpo. Isso pode levar a v\u00e1rias condi\u00e7\u00f5es de sa\u00fade, incluindo condronecrose bacteriana e osteomielite (BCO). Essa condi\u00e7\u00e3o ocorre quando bact\u00e9rias nocivas na corrente sangu\u00ednea se instalam em microfraturas entre as placas de crescimento e a cartilagem articular do f\u00eamur, da t\u00edbia e das v\u00e9rtebras tor\u00e1cicas flex\u00edveis, levando a microabscessos e necrose. <\/p>\n\n\n\n

A BCO \u00e9 a causa mais comum de claudica\u00e7\u00e3o em aves dom\u00e9sticas em todo o mundo, especialmente em lotes que n\u00e3o s\u00e3o tratados com antibi\u00f3ticos. As perdas financeiras causadas pela BCO variam de 1% a 3% em condi\u00e7\u00f5es normais, ou de 10% a 15% em casos extremos, causando impacto no abate, crescimento mais lento e condena\u00e7\u00e3o. <\/p>\n\n\n\n

Leia mais: BCO em aves - Quanto est\u00e1 custando \u00e0 sua opera\u00e7\u00e3o?<\/a> <\/p>\n\n\n\n

As bact\u00e9rias s\u00e3o os organismos dominantes do mundo, ainda mais do que os seres humanos. Muitas esp\u00e9cies de bact\u00e9rias causam a BCO, mas as mais frequentemente encontradas s\u00e3o aquelas que s\u00e3o familiares aos produtores e consumidores de aves, incluindo Enterococcus ssp<\/em>., E. cecorum<\/em>, Staphylococcus<\/em> spp. e S. agnetis<\/em> entre outros. H\u00e1 relatos sobre a recupera\u00e7\u00e3o de Salmonella de ossos. Essas bact\u00e9rias podem romper o tecido epitelial, sobreviver \u00e0s respostas inflamat\u00f3rias e imunol\u00f3gicas e, por fim, ser depositadas em locais remotos onde a presen\u00e7a de c\u00e9lulas imunol\u00f3gicas e fag\u00f3citos \u00e9 limitada, a irriga\u00e7\u00e3o \u00e9 reduzida ou o epit\u00e9lio vascular \u00e9 fraco. <\/p>\n\n\n\n

O primeiro passo para retardar o aparecimento e reduzir a preval\u00eancia da BCO em lotes de aves \u00e9 melhorar a integridade da primeira linha de defesa: o tecido epitelial. <\/p>\n\n\n\n

Qual \u00e9 a fun\u00e7\u00e3o do tecido epitelial?<\/h3>\n\n\n\n

O tecido epitelial<\/strong> cobre o corpo por fora e por dentro dos \u00f3rg\u00e3os tubulares. Ele inclui a pele e o revestimento epitelial no trato gastrointestinal, no sistema respirat\u00f3rio, no sistema reprodutivo e outros, at\u00e9 mesmo o endot\u00e9lio vascular que cobre os vasos sangu\u00edneos. O tecido epitelial \u00e9 uma parede s\u00f3lida com c\u00e9lulas ligadas por jun\u00e7\u00f5es estreitas. Essas c\u00e9lulas s\u00e3o continuamente renovadas, e algumas delas produzem muco e componentes secret\u00f3rios de prote\u00e7\u00e3o. Quando essas c\u00e9lulas s\u00e3o danificadas por estresse, parasitas ou bact\u00e9rias, elas devem ser substitu\u00eddas imediatamente para manter a integridade do epit\u00e9lio e garantir que esses parasitas n\u00e3o consigam penetrar no corpo. <\/p>\n\n\n\n

Portanto, essas prote\u00ednas celulares precisam ser sintetizadas continuamente. Se n\u00e3o houver um pool adequado de novas c\u00e9lulas epiteliais para substituir imediatamente as danificadas, as bact\u00e9rias ter\u00e3o a oportunidade de entrar na corrente sangu\u00ednea. <\/p>\n\n\n\n

Os minerais residuais, como o zinco, o mangan\u00eas e o cobre, s\u00e3o essenciais para a produ\u00e7\u00e3o e a manuten\u00e7\u00e3o dos tecidos epiteliais. As prote\u00ednas de jun\u00e7\u00e3o estreita, como ZO1, ZO2, claudina e oclus\u00e3o, exigem zinco para sua s\u00edntese. Para manter uma camada protetora e a estrutura celular, as c\u00e9lulas epiteliais cont\u00eam uma matriz de citoesqueleto composta de col\u00e1geno e filamentos de queratina ou fibras de prote\u00edna firmemente enroladas. A principal fun\u00e7\u00e3o da queratina \u00e9 tornar a pele uma barreira male\u00e1vel, insol\u00favel e n\u00e3o reativa contra o ambiente natural. O zinco \u00e9 um mineral essencial no processo de queratiniza\u00e7\u00e3o. <\/p>\n\n\n\n

Melhore a fun\u00e7\u00e3o do tecido epitelial com suplementos de minerais residuais<\/h2>\n\n\n\n

Os minerais residuais em Availa\u00aeZMC<\/a> - zinco, mangan\u00eas e cobre - melhoram a integridade intestinal, fortalecendo as jun\u00e7\u00f5es estreitas do intestino para que as bact\u00e9rias n\u00e3o saiam e se instalem nas microfraturas das placas de crescimento. Esses minerais tamb\u00e9m ajudam a melhorar a qualidade dos ossos e a sa\u00fade geral e a fun\u00e7\u00e3o imunol\u00f3gica das aves. <\/p>\n\n\n\n

Leia mais: BCO Lameness in Chickens: A ponta de um iceberg<\/a> <\/p>\n\n\n\n

Um estudo de pesquisa realizado na Universidade de Arkansas usando um modelo de desafio rigoroso resultou em uma redu\u00e7\u00e3o significativa na preval\u00eancia de claudica\u00e7\u00e3o por BCO e atrasou a incid\u00eancia em quatro a cinco dias. As aves alimentadas com Availa-ZMC em modelos de piso de arame tiveram uma redu\u00e7\u00e3o de 29% na claudica\u00e7\u00e3o da BCO. E as aves alimentadas com Availa-ZMC em um modelo de piso de cama exposto a Staphylococcus agnetis<\/em>O teste de sensibilidade do animal, que foi realizado em um ano, mostrou uma redu\u00e7\u00e3o de 23% na claudica\u00e7\u00e3o. Houve tamb\u00e9m uma redu\u00e7\u00e3o na gravidade da necrose da cabe\u00e7a da t\u00edbia e do f\u00eamur. Isso se deve, em grande parte, ao desempenho aprimorado que os minerais residuais proporcionam \u00e0s c\u00e9lulas epiteliais. <\/p>\n\n\n\n

A fun\u00e7\u00e3o adequada do tecido epitelial pode reduzir a condronecrose bacteriana e a osteomielite em aves dom\u00e9sticas<\/h2>\n\n\n\n

Garantir uma barreira epitelial forte \u00e9 o primeiro passo essencial para reduzir a preval\u00eancia de BCO em seu lote de aves. Se voc\u00ea puder garantir que as aves tenham um conjunto adequado de novas c\u00e9lulas totalmente funcionais para substituir as danificadas pelas bact\u00e9rias, ser\u00e1 poss\u00edvel impedir que essas bact\u00e9rias entrem na corrente sangu\u00ednea. <\/p>\n\n\n\n

Para saber mais sobre como formular seu programa de nutri\u00e7\u00e3o de aves para melhorar a integridade epitelial e prevenir a BCO, Entre em contato com seu representante Zinpro hoje mesmo.<\/a> <\/p>","protected":false},"excerpt":{"rendered":"

A condronecrose bacteriana e a osteomielite (BCO) s\u00e3o a causa mais comum de claudica\u00e7\u00e3o em aves dom\u00e9sticas em todo o mundo. Saiba como melhorar a integridade epitelial \u00e9 a primeira linha de defesa contra essa condi\u00e7\u00e3o infecciosa.<\/p>","protected":false},"author":33,"featured_media":57322,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_tec_requires_first_save":true,"_eb_attr":"","_uag_custom_page_level_css":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[2682],"tags":[2692,2696,2688,2686,2690,2704],"species":[942],"class_list":["post-57321","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-animal-welfare","tag-epithelial-integrity","tag-gut-health","tag-inflammation","tag-lameness","tag-meat-carcass-quality"],"acf":[],"yoast_head":"\nProper 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