{"id":56096,"date":"2018-10-04T02:50:22","date_gmt":"2018-10-04T02:50:22","guid":{"rendered":"https:\/\/www.zinpro.com\/reducing-leaky-gut-intestinal-inflammation-in-poultry-with-zinc\/"},"modified":"2023-07-19T13:09:34","modified_gmt":"2023-07-19T18:09:34","slug":"reducing-leaky-gut-intestinal-inflammation-in-poultry-with-zinc","status":"publish","type":"post","link":"https:\/\/www.zinpro.com\/pt\/resource-center\/blog\/reducing-leaky-gut-intestinal-inflammation-in-poultry-with-zinc\/","title":{"rendered":"Reduzindo o intestino perme\u00e1vel e a inflama\u00e7\u00e3o intestinal em aves dom\u00e9sticas com zinco"},"content":{"rendered":"<p>A inflama\u00e7\u00e3o intestinal \u00e9 uma condi\u00e7\u00e3o que causa uma aspereza no trato gastrointestinal da ave, prejudicando sua capacidade de absorver nutrientes e atingir seu potencial gen\u00e9tico e de crescimento. Infec\u00e7\u00f5es, traumas, brigas, bicadas e outros fatores ambientais podem causar inflama\u00e7\u00e3o intestinal. Mas uma das principais causas pode ser a dieta da ave, pois alguns ingredientes da ra\u00e7\u00e3o, como farelo de soja, trigo e centeio, podem causar dist\u00farbios intestinais, o que pode levar \u00e0 inflama\u00e7\u00e3o.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-what-is-leaky-gut-in-poultry\">O que \u00e9 intestino perme\u00e1vel em aves?<\/h3>\n\n\n\n<p>O revestimento do trato intestinal \u00e9 composto por uma camada de c\u00e9lulas epiteliais. Essas c\u00e9lulas s\u00e3o ligadas umas \u00e0s outras por estruturas proteicas complexas chamadas de \"jun\u00e7\u00f5es estreitas\", e sua fun\u00e7\u00e3o \u00e9 evitar que bact\u00e9rias, pat\u00f3genos e toxinas passem pelo revestimento intestinal e entrem na corrente sangu\u00ednea.<\/p>\n\n\n\n<p>Fatores como estresse t\u00e9rmico, bact\u00e9rias, contaminantes alimentares, etc., podem enfraquecer a qualidade das jun\u00e7\u00f5es estreitas, levando a uma s\u00edndrome chamada \"intestino perme\u00e1vel\". Esse impacto negativo - intestino perme\u00e1vel - permite que bact\u00e9rias, agentes patog\u00eanicos e toxinas passem entre as c\u00e9lulas epiteliais, resultando em danos celulares ou inflama\u00e7\u00e3o do intestino.<\/p>\n\n\n\n<p>Quando as bact\u00e9rias, os agentes patog\u00eanicos ou as toxinas passam entre as c\u00e9lulas, o sistema imunol\u00f3gico os reconhece e aciona uma resposta imunol\u00f3gica para eliminar o desafio. Essa inflama\u00e7\u00e3o - ativa\u00e7\u00e3o do sistema imunol\u00f3gico - consumir\u00e1 quantidades significativas de nutrientes para lidar com a inflama\u00e7\u00e3o, reduzindo a quantidade de nutrientes dispon\u00edveis para o crescimento muscular.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-how-does-zinc-mitigate-leaky-gut-in-poultry\">Como o zinco atenua o intestino perme\u00e1vel em aves?<\/h3>\n\n\n\n<p>H\u00e1 dois caminhos pelos quais o zinco atenua a inflama\u00e7\u00e3o. Primeiro, ele fortalece as liga\u00e7\u00f5es entre as c\u00e9lulas epiteliais no trato gastrointestinal, ajudando a manter as \"jun\u00e7\u00f5es apertadas\" durante um desafio e diminuindo a ocorr\u00eancia de intestino perme\u00e1vel e inflama\u00e7\u00e3o. Em segundo lugar, o zinco ajuda a fortalecer o sistema imunol\u00f3gico, de modo que, quando ocorre um desafio, o sistema imunol\u00f3gico pode responder de maneira mais r\u00e1pida e robusta.<\/p>\n\n\n\n<p>Para demonstrar como o zinco pode ajudar os frangos de corte a lidar melhor com a inflama\u00e7\u00e3o intestinal e o estresse oxidativo, a Zinpro fez uma parceria com a Universidade de Ghent, na B\u00e9lgica, para testar se o zinco de <a href=\"https:\/\/www.zinpro.com\/pt\/products\/availa-mins\/availa-zn\/\" target=\"_blank\" rel=\"noreferrer noopener\">Zinpro Availa<sup>\u00ae<\/sup> Zn<\/a> \u00e9 superior ao sulfato de zinco na preserva\u00e7\u00e3o da morfologia intestinal em aves afetadas por disbiose, um desequil\u00edbrio entre bact\u00e9rias boas e ruins devido a um desafio alimentar.<\/p>\n\n\n\n<p>O estudo envolveu 680 frangos de um dia de idade que foram alimentados com uma dieta \u00e0 base de trigo e centeio por um per\u00edodo de 36 dias para iniciar um desafio intestinal. Para garantir a forma\u00e7\u00e3o de um desafio intestinal, os frangos n\u00e3o receberam uma enzima NSP, que \u00e9 uma suplementa\u00e7\u00e3o padr\u00e3o ao alimentar com trigo, cevada ou centeio na dieta. O zinco do Availa-Zn foi fornecido a 340 dos frangos de corte a uma taxa de 60 ppm, enquanto os 340 frangos restantes receberam 60 ppm de sulfato de zinco durante o estudo de 36 dias.<\/p>\n\n\n\n<p>As amostras de tecido duodenal foram coletadas no dia 28 e as amostras de sangue foram coletadas aos 36 dias de idade.<\/p>\n\n\n\n<p>Os frangos de corte alimentados com Availa<sup>\u00ae<\/sup> O Zn aumentou o comprimento das vilosidades e a propor\u00e7\u00e3o entre vilosidades e profundidade da cripta aos 28 dias de idade. O maior comprimento das vilosidades e a maior propor\u00e7\u00e3o indicam que os frangos alimentados com zinco do Availa-Zn n\u00e3o sofreram tanto com a inflama\u00e7\u00e3o intestinal causada pela dieta de trigo e centeio, em compara\u00e7\u00e3o com os frangos alimentados com sulfato de zinco.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"http:\/\/www.zinpro.com\/wp-content\/uploads\/2023\/06\/Chart-1-1024x279-1.jpg\" alt=\"\" class=\"wp-image-15277\"\/><\/figure>\n\n\n\n<p>Uma segunda descoberta importante do estudo indicou uma diminui\u00e7\u00e3o na atividade da glutationa peroxidase (GPx) no plasma aos 36 dias de idade. A glutationa peroxidase \u00e9 uma enzima que faz parte do sistema antioxidante do corpo. Quando ocorre uma inflama\u00e7\u00e3o, o corpo reage \u00e0 inflama\u00e7\u00e3o e aumenta a produ\u00e7\u00e3o de antioxidantes e da glutationa peroxidase. Um n\u00edvel mais baixo de glutationa peroxidase significa que os frangos de corte alimentados com zinco do Availa-Zn tiveram uma necessidade menor de antioxidantes porque sofreram menos inflama\u00e7\u00e3o no trato gastrointestinal. Isso indica que o zinco do Availa-Zn est\u00e1 ajudando a poupar o sistema antioxidante durante um desafio de inflama\u00e7\u00e3o.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"http:\/\/www.zinpro.com\/wp-content\/uploads\/2023\/06\/Chart-2-1024x262-1.jpg\" alt=\"\" class=\"wp-image-15281\"\/><\/figure>\n\n\n\n<p>Uma terceira descoberta mostra uma melhora na taxa de convers\u00e3o alimentar dos frangos de corte alimentados com zinco da Availa-Zn. Apesar do desafio da inflama\u00e7\u00e3o intestinal, os frangos alimentados com zinco do Availa-Zn consumiram menos ra\u00e7\u00e3o por quilograma de ganho de peso corporal, o que significa que as aves foram mais eficientes no uso dos nutrientes da ra\u00e7\u00e3o para produzir tecido muscular. Essa \u00e9 uma indica\u00e7\u00e3o indireta de que as aves alimentadas com zinco da Availa-Zn sofreram menos inflama\u00e7\u00e3o intestinal devido \u00e0 dieta de trigo e centeio.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-bottom-line-zinc-from-availa-zn-reduces-intestinal-inflammation\">Conclus\u00e3o: O zinco do Availa-Zn reduz a inflama\u00e7\u00e3o intestinal<\/h3>\n\n\n\n<p>A inflama\u00e7\u00e3o e a resposta do corpo \u00e0 inflama\u00e7\u00e3o t\u00eam um custo. Ao alimentar o zinco de <a href=\"https:\/\/www.zinpro.com\/pt\/products\/availa-mins\/availa-zn\/\" target=\"_blank\" rel=\"noreferrer noopener\">Dispon\u00edvel - Zn<\/a> para aves, os produtores podem diminuir o impacto da inflama\u00e7\u00e3o. Isso ajuda a garantir que os nutrientes estejam sendo usados para o crescimento e o desenvolvimento muscular, em vez de combater um desafio de inflama\u00e7\u00e3o.<\/p>\n\n\n\n<p><a href=\"https:\/\/www.zinpro.com\/pt\/contact-us\/\" target=\"_blank\" rel=\"noreferrer noopener\">Entre em contato com seu representante Zinpro<\/a> para saber mais sobre os minerais tra\u00e7o de desempenho e seu papel no controle da inflama\u00e7\u00e3o intestinal em sua cria\u00e7\u00e3o de aves.<\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>A inflama\u00e7\u00e3o intestinal est\u00e1 afetando o desempenho de sua opera\u00e7\u00e3o av\u00edcola? Leia este artigo para saber mais e descubra como a alimenta\u00e7\u00e3o com minerais tra\u00e7o de desempenho garante que os nutrientes sejam usados para o crescimento e o desenvolvimento muscular, em vez de combater um desafio de inflama\u00e7\u00e3o.<\/p>","protected":false},"author":48,"featured_media":55878,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_tec_requires_first_save":true,"_eb_attr":"","_uag_custom_page_level_css":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[2682],"tags":[2702,2696,2688,2686],"species":[942],"class_list":["post-56096","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-antibiotic-free-production","tag-epithelial-integrity","tag-gut-health","tag-inflammation"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Reducing Leaky Gut &amp; Intestinal Inflammation in Poultry with Zinc &#8211; Zinpro\u00ae<\/title>\n<meta name=\"description\" content=\"posts from Zinpro\u00ae about Reducing Leaky Gut &amp; Intestinal Inflammation in Poultry with Zinc . 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