{"id":56027,"date":"2018-10-03T23:41:40","date_gmt":"2018-10-03T23:41:40","guid":{"rendered":"https:\/\/www.zinpro.com\/swine-nutrition-impacts-piglet-gut-health-and-immune-response\/"},"modified":"2024-09-05T11:02:32","modified_gmt":"2024-09-05T16:02:32","slug":"swine-nutrition-impacts-piglet-gut-health-and-immune-response","status":"publish","type":"post","link":"https:\/\/www.zinpro.com\/pt\/resource-center\/blog\/swine-nutrition-impacts-piglet-gut-health-and-immune-response\/","title":{"rendered":"A nutri\u00e7\u00e3o de su\u00ednos afeta a sa\u00fade intestinal e a resposta imunol\u00f3gica dos leit\u00f5es"},"content":{"rendered":"

Um dos maiores desafios do setor de su\u00ednos \u00e9 a capacidade de sobreviv\u00eancia e o desempenho dos leit\u00f5es. O estresse do desmame e a perda da imunidade passiva do leite da porca aumentam a suscetibilidade dos su\u00ednos rec\u00e9m-desmamados a bact\u00e9rias intestinais infecciosas, criando desafios para a sobreviv\u00eancia geral.<\/p>\n\n\n\n

A taxa m\u00e9dia de mortalidade antes do desmame nos Estados Unidos \u00e9 de cerca de 16%, com grande varia\u00e7\u00e3o e oportunidade de melhoria. Portanto, garantir que os leit\u00f5es desenvolvam uma boa sa\u00fade intestinal e uma resposta imunol\u00f3gica robusta \u00e9 vital para a sobreviv\u00eancia.<\/p>\n\n\n\n

Pesquisas demonstraram que, ao suplementar marr\u00e3s e porcas em gesta\u00e7\u00e3o com minerais de desempenho, observamos uma melhor resposta de desempenho e um impacto duradouro na prole, ajudando a melhorar a integridade intestinal.<\/p>\n\n\n\n

Preven\u00e7\u00e3o de intestino perme\u00e1vel por meio de uma nutri\u00e7\u00e3o aprimorada de minerais tra\u00e7os<\/h3>\n\n\n\n

O revestimento do trato intestinal \u00e9 composto por v\u00e1rias camadas de tecido epitelial. As vilosidades, ou estruturas de absor\u00e7\u00e3o do intestino, s\u00e3o revestidas por enter\u00f3citos, que \u00e9 onde os nutrientes s\u00e3o absorvidos. Essas c\u00e9lulas s\u00e3o ligadas umas \u00e0s outras por estruturas proteicas complexas, uma das quais s\u00e3o as \"jun\u00e7\u00f5es estreitas\". Sua fun\u00e7\u00e3o \u00e9 evitar que bact\u00e9rias, pat\u00f3genos e toxinas passem entre os enter\u00f3citos e entrem na corrente sangu\u00ednea, ajudando a criar uma barreira f\u00edsica protetora.<\/p>\n\n\n\n

Uma parede intestinal saud\u00e1vel tem vilosidades longas, em forma de dedo, que proporcionam uma grande superf\u00edcie para a digest\u00e3o e absor\u00e7\u00e3o de nutrientes. Antes do desmame, as vilosidades intestinais (respons\u00e1veis pela absor\u00e7\u00e3o de nutrientes) s\u00e3o finas e alongadas, ao passo que, ap\u00f3s o desmame, a altura das vilosidades diminui cerca de 75% durante as primeiras 24 horas ap\u00f3s o desmame, tornando-se rapidamente grossas e curtas. As vilosidades encurtadas podem prejudicar a digest\u00e3o e a absor\u00e7\u00e3o de nutrientes. A redu\u00e7\u00e3o da ingest\u00e3o de nutrientes tamb\u00e9m compromete a integridade das jun\u00e7\u00f5es estreitas.<\/p>\n\n\n\n

Fatores como estresse t\u00e9rmico, redu\u00e7\u00e3o do consumo de ra\u00e7\u00e3o, bact\u00e9rias, contaminantes da ra\u00e7\u00e3o, etc., podem enfraquecer a qualidade das jun\u00e7\u00f5es estreitas, levando a uma s\u00edndrome chamada \"intestino perme\u00e1vel\". Essa condi\u00e7\u00e3o - leaky gut - permite que mol\u00e9culas como bact\u00e9rias, pat\u00f3genos e toxinas passem entre as c\u00e9lulas epiteliais, resultando em danos celulares e inflama\u00e7\u00e3o do intestino. Quando isso ocorre, o sistema imunol\u00f3gico \u00e9 acionado, o que exige n\u00edveis significativos de nutrientes para lidar com a inflama\u00e7\u00e3o, reduzindo a quantidade de nutrientes dispon\u00edveis para o crescimento dos leit\u00f5es.<\/p>\n\n\n\n

Pesquisas demonstraram que a nutri\u00e7\u00e3o de uma gera\u00e7\u00e3o pode ter um impacto positivo ou negativo na nutri\u00e7\u00e3o da gera\u00e7\u00e3o seguinte. Isso se aplica tanto a humanos quanto a animais. A Zinpro fez uma parceria com a Universidade de Alberta (Caine et al., 2009) para avaliar como a incorpora\u00e7\u00e3o de minerais de desempenho na dieta da porca em gesta\u00e7\u00e3o pode ajudar o leit\u00e3o a desenvolver uma resposta imunol\u00f3gica inicial mais robusta.<\/p>\n\n\n\n

As porcas foram divididas em dois grupos e alimentadas com minerais inorg\u00e2nicos ou minerais de tra\u00e7o de desempenho<\/a> durante o \u00faltimo est\u00e1gio da gesta\u00e7\u00e3o (d 80 a 114):<\/p>\n\n\n\n

Tratamento inorg\u00e2nico:<\/strong> 120 ppm de Zn do \u00f3xido de zinco (ZnO)
Zinpro<\/b>\u00ae<\/b><\/sup> Zinpro Availa\u00ae<\/sup> Tratamento com zinco:<\/strong> 250 ppm de zinco de Zinpro Availa Zinco<\/a> adicionados \u00e0 dieta de controle dos dias 80 a 114 de gesta\u00e7\u00e3o.<\/p>\n\n\n\n

Depois que as porcas pariram a ninhada, elas passaram a receber uma dieta comum de lacta\u00e7\u00e3o e os leit\u00f5es foram colhidos aos 14 dias de idade para observar a morfologia intestinal.<\/p>\n\n\n\n

Embora tenha sido demonstrado que a altura das vilosidades diminui cerca de 75% durante as primeiras 24 horas ap\u00f3s o desmame, tornando-se rapidamente espessas e curtas, os leit\u00f5es nascidos de porcas que receberam zinco do Zinpro Availa Zinc apresentaram maior altura das vilosidades intestinais e maior rela\u00e7\u00e3o entre altura das vilosidades e profundidade da cripta. Isso resultou em uma superf\u00edcie de absor\u00e7\u00e3o maior para o leit\u00e3o absorver nutrientes, al\u00e9m de ajudar a reduzir a incid\u00eancia de diarreia.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Uma resposta imunol\u00f3gica mais robusta<\/h3>\n\n\n\n

A morfologia intestinal tamb\u00e9m mostrou um aumento nos linf\u00f3citos intraepiteliais, que ajudam a eliminar c\u00e9lulas epiteliais intestinais danificadas ou infectadas. Isso, por sua vez, ajuda a melhorar a resposta imunol\u00f3gica intestinal do porco. Tamb\u00e9m houve um aumento nas c\u00e9lulas caliciformes no intestino. As c\u00e9lulas caliciformes s\u00e3o respons\u00e1veis pela produ\u00e7\u00e3o de mucina, e a mucina cria a camada de muco ao longo das paredes do intestino. Os linf\u00f3citos intraepiteliais t\u00eam como alvo e destroem os agentes patog\u00eanicos para ajudar a reduzir a carga geral de agentes patog\u00eanicos. As c\u00e9lulas caliciformes s\u00e3o respons\u00e1veis pela produ\u00e7\u00e3o de mucina, que ajuda a atuar como uma barreira mucosa protetora para o revestimento do intestino.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Para saber mais sobre os minerais de desempenho e seu papel na sa\u00fade intestinal dos leit\u00f5es, Entre em contato com seu representante Zinpro<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"

A taxa m\u00e9dia de mortalidade antes do desmame nos Estados Unidos \u00e9 de cerca de 16%, com grande varia\u00e7\u00e3o e oportunidade de melhoria. Portanto, garantir que os leit\u00f5es desenvolvam uma boa sa\u00fade intestinal e uma resposta imunol\u00f3gica inicial robusta durante um desafio \u00e9 vital para a sobreviv\u00eancia. Saiba como a alimenta\u00e7\u00e3o de porcas em gesta\u00e7\u00e3o com minerais de alto desempenho pode ajudar a melhorar a sa\u00fade intestinal e apoiar uma resposta imunol\u00f3gica robusta nos leit\u00f5es.<\/p>","protected":false},"author":74,"featured_media":55848,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_tec_requires_first_save":true,"_eb_attr":"","_uag_custom_page_level_css":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[2682],"tags":[2683,2688,2684,2689,2685,2687],"species":[943],"class_list":["post-56027","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-animal-performance","tag-gut-health","tag-health","tag-heat-stress","tag-immunity","tag-milk-quality"],"acf":[],"yoast_head":"\nSwine Nutrition Impacts Piglet Gut Health and Immune Response – Zinpro\u00ae<\/title>\n<meta name=\"description\" content=\"Blog posts from Zinpro\u00ae about Swine Nutrition Impacts Piglet Gut Health and Immune Response . 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