{"id":57590,"date":"2021-09-29T12:45:10","date_gmt":"2021-09-29T12:45:10","guid":{"rendered":"https:\/\/www.zinpro.com\/manage-prrs-in-pigs-with-zinc\/"},"modified":"2024-09-09T13:23:16","modified_gmt":"2024-09-09T18:23:16","slug":"manage-prrs-in-pigs-with-zinc","status":"publish","type":"post","link":"https:\/\/www.zinpro.com\/pl\/resource-center\/blog\/manage-prrs-in-pigs-with-zinc\/","title":{"rendered":"Ogranicz replikacj\u0119 wirusa PRRS u \u015bwi\u0144 dzi\u0119ki sprawdzonemu \u017cywieniu"},"content":{"rendered":"

Zazwyczaj zesp\u00f3\u0142 rozrodczo-oddechowy \u015bwi\u0144 (PRRS) jest wirusem sezonowym w stadach \u015bwi\u0144. Zwykle nasila si\u0119 mi\u0119dzy pa\u017adziernikiem a kwietniem i s\u0142abnie w miesi\u0105cach letnich.  <\/p>\n\n\n\n

Ale nie by\u0142o tak przez ostatnie kilka lat. PRRS utrzymywa\u0142 si\u0119 przez ca\u0142e lato z nowymi szczepami, kt\u00f3re wydaj\u0105 si\u0119 by\u0107 bardziej dotkliwe ni\u017c zwykle. Opr\u00f3cz powodowania zwyk\u0142ych problem\u00f3w reprodukcyjnych, te szczepy PRRS wygenerowa\u0142y wy\u017cszy wska\u017anik \u015bmiertelno\u015bci zar\u00f3wno u loch, jak i \u015bwi\u0144 hodowlanych, pozostawiaj\u0105c wielu z nas w bran\u017cy pytanie, czy nasilenie PRRS b\u0119dzie nadal ros\u0142o.  <\/p>\n\n\n\n

Zrozumienie replikacji wirus\u00f3w RNA, takich jak PRRS <\/em><\/strong> <\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

PRRS, podobnie jak inne wirusy wyst\u0119puj\u0105ce u zwierz\u0105t i ludzi, mo\u017ce by\u0107 przenoszony przez bliski kontakt przez nos lub usta lub przez powietrze. Gdy wirus znajdzie si\u0119 wewn\u0105trz \u015bwini, zaczyna atakowa\u0107 kom\u00f3rki odporno\u015bciowe w p\u0142ucach i walczy\u0107 z uk\u0142adem odporno\u015bciowym.  <\/p>\n\n\n\n

Je\u015bli odpowied\u017a immunologiczna nie jest wystarczaj\u0105co szybka, aby odebra\u0107 kom\u00f3rki wirusowi PRRS, uk\u0142ad odporno\u015bciowy zabije te kom\u00f3rki, aby uratowa\u0107 reszt\u0119 \u015bwini. Przy mniejszej liczbie dost\u0119pnych kom\u00f3rek odporno\u015bciowych zmniejsza to zdolno\u015b\u0107 \u015bwini do zwalczania dodatkowych infekcji lub innych chor\u00f3b, takich jak grypa. Gdy to wszystko si\u0119 dzieje, wirus b\u0119dzie nadal si\u0119 replikowa\u0142 i rozprzestrzenia\u0142 na inne kom\u00f3rki odporno\u015bciowe w p\u0142ucach.  <\/p>\n\n\n\n

Podobnie jak grypa \u015bwi\u0144, rotawirusy i koronawirusy, PRRS jest wirusem RNA. Oznacza to, \u017ce sk\u0142ada si\u0119 on z pojedynczej nici materia\u0142u genetycznego RNA, w przeciwie\u0144stwie do wirus\u00f3w DNA, kt\u00f3re zawieraj\u0105 wiele splecionych ze sob\u0105 nici.  <\/p>\n\n\n\n

Poniewa\u017c wirusy RNA sk\u0142adaj\u0105 si\u0119 z jednej nici, \u0142atwiej jest im mutowa\u0107 lub tworzy\u0107 r\u00f3\u017cne wersje. Te r\u00f3\u017cne szczepy mog\u0105 utrudnia\u0107 leczenie lub szczepienie, poniewa\u017c szczepionki s\u0105 zwykle wytwarzane dla okre\u015blonego szczepu.  <\/p>\n\n\n\n

Spowolnij PRRS u \u015bwi\u0144 dzi\u0119ki sprawdzonemu \u017cywieniu minera\u0142ami \u015bladowymi<\/strong><\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Chocia\u017c istnieje wiele metod zapobiegania PRRS, takich jak szczepionki i poprawa \u015brodk\u00f3w bezpiecze\u0144stwa biologicznego, prawid\u0142owe od\u017cywianie pomaga r\u00f3wnie\u017c odzyska\u0107 kontrol\u0119 nad zdrowiem \u015bwi\u0144. W szczeg\u00f3lno\u015bci badania wykaza\u0142y, \u017ce cynk spowalnia replikacj\u0119 wirus\u00f3w<\/a>.1<\/sup>    <\/p>\n\n\n\n

Kiedy wirus RNA replikuje si\u0119, enzym zwany polimeraz\u0105 RNA przepisuje wirusowe DNA na wi\u0119cej wirusowego RNA, umo\u017cliwiaj\u0105c mu rozprzestrzenianie si\u0119 do innych kom\u00f3rek. Aby to zrobi\u0107, potrzebuje dwuwarto\u015bciowego jonu metalu lub metalu z 2+. Jednym z przyk\u0142ad\u00f3w jest magnez (Mg2+). Magnez jest nadal wa\u017cnym sk\u0142adnikiem od\u017cywczym dla wielu funkcji w organizmie \u015bwini, ale musi by\u0107 w odpowiedniej r\u00f3wnowadze. W tej sytuacji polimeraza RNA jest jak poci\u0105g, a magnez jest tym, co buduje tory, aby mog\u0142a dalej jecha\u0107 i produkowa\u0107 wi\u0119cej wirus\u00f3w.    <\/p>\n\n\n\n

<\/p>\n\n\n\n

Cynk Zinpro\u00ae mo\u017ce jednak zast\u0105pi\u0107 magnez, spowalniaj\u0105c produkcj\u0119 \u015blad\u00f3w i znacznie ograniczaj\u0105c replikacj\u0119 wirusa. Reakcja replikacji wewn\u0105trz kom\u00f3rki preferuje cynk w stosunku do magnezu. Aby cynk by\u0142 preferencyjnie wykorzystywany w tej reakcji i os\u0142abia\u0142 replikacj\u0119 wirusa, cynk musi znajdowa\u0107 si\u0119 wewn\u0105trz kom\u00f3rki. Polimeraza RNA ma wi\u0119ksze powinowactwo do cynku ni\u017c manganu. Je\u015bli cynk jest dost\u0119pny, kom\u00f3rki wci\u0105gn\u0105 go, aby rozpocz\u0105\u0107 prac\u0119, zanim magnez b\u0119dzie mia\u0142 szans\u0119. <\/p>\n\n\n\n

Zapewnij \u015bwiniom przewag\u0119 dzi\u0119ki niezr\u00f3wnanemu wch\u0142anianiu minera\u0142\u00f3w \u015bladowych<\/strong> <\/strong><\/strong><\/strong><\/strong><\/strong><\/h2>\n\n\n\n

Zapewniasz swoim \u015bwiniom przewag\u0119, gdy karmisz je odpowiednim cynkiem z Zinpro Performance Minerals\u00ae<\/sup><\/a>. Cynk Zinpro jest najbardziej dost\u0119pnym metabolicznie \u017ar\u00f3d\u0142em cynku na rynku, dzi\u0119ki czemu jego wi\u0119ksza ilo\u015b\u0107 dociera do kom\u00f3rek odporno\u015bciowych i pomaga ograniczy\u0107 replikacj\u0119 wirus\u00f3w, takich jak PRRS.   <\/p>\n\n\n\n

Aby dowiedzie\u0107 si\u0119 wi\u0119cej o tym, jak nasze produkty i rozwi\u0105zania mog\u0105 zapobiega\u0107 i zarz\u0105dza\u0107 ogniskami PRRS w stadzie \u015bwi\u0144, Skontaktuj si\u0119 z przedstawicielem Zinpro ju\u017c dzi\u015b<\/a>.  <\/p>\n\n\n\n

\u0179r\u00f3d\u0142a<\/strong> <\/strong><\/h2>\n\n\n\n

1<\/sup> te Velthuis AJW, van den Worm SHE, Sims AC, Baric RS, Snijder EJ, van Hemert MJ (2010) Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture. PLoS Pathog 6(11): e1001176. https:\/\/doi.org\/10.1371\/journal.ppat.1001176. <\/p>","protected":false},"excerpt":{"rendered":"

Typically, porcine reproductive and respiratory syndrome, or PRRS, is a seasonal virus in pig herds. It usually spikes between October and April and wanes during […]<\/p>\n","protected":false},"author":104,"featured_media":57591,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_tec_requires_first_save":true,"_eb_attr":"","_uag_custom_page_level_css":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[2682],"tags":[2683,2692,2684,2685,2694,2712],"species":[943],"class_list":["post-57590","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-animal-performance","tag-animal-welfare","tag-health","tag-immunity","tag-mortality","tag-respiratory"],"acf":[],"yoast_head":"\nManage PRRS in Pigs with Zinc Trace Mineral Supplements | Zinpro<\/title>\n<meta name=\"description\" content=\"The PRRS virus is often seasonal in pig herds, but this year it has persisted. 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