{"id":56027,"date":"2018-10-03T23:41:40","date_gmt":"2018-10-03T23:41:40","guid":{"rendered":"https:\/\/www.zinpro.com\/swine-nutrition-impacts-piglet-gut-health-and-immune-response\/"},"modified":"2024-09-05T11:02:32","modified_gmt":"2024-09-05T16:02:32","slug":"swine-nutrition-impacts-piglet-gut-health-and-immune-response","status":"publish","type":"post","link":"https:\/\/www.zinpro.com\/fr\/resource-center\/blog\/swine-nutrition-impacts-piglet-gut-health-and-immune-response\/","title":{"rendered":"L'alimentation des porcs a un impact sur la sant\u00e9 intestinale et la r\u00e9ponse immunitaire des porcelets"},"content":{"rendered":"

L'un des plus grands d\u00e9fis de l'industrie porcine est la survie et la performance des porcelets. Le stress du sevrage et la perte de l'immunit\u00e9 passive du lait de la truie augmentent la sensibilit\u00e9 des porcs nouvellement sevr\u00e9s aux bact\u00e9ries intestinales infectieuses, ce qui pose des probl\u00e8mes de survie globale.<\/p>\n\n\n\n

Le taux moyen de mortalit\u00e9 avant sevrage aux \u00c9tats-Unis est d'environ 16 %, avec de fortes variations et des possibilit\u00e9s d'am\u00e9lioration. Il est donc essentiel pour la survie des porcelets de s'assurer qu'ils d\u00e9veloppent une bonne sant\u00e9 intestinale et une r\u00e9ponse immunitaire robuste.<\/p>\n\n\n\n

La recherche a montr\u00e9 qu'en suppl\u00e9mentant les cochettes et les truies en gestation avec des oligo-\u00e9l\u00e9ments de performance, nous constatons une am\u00e9lioration des performances et un impact durable sur la prog\u00e9niture en aidant \u00e0 am\u00e9liorer l'int\u00e9grit\u00e9 de l'intestin.<\/p>\n\n\n\n

Pr\u00e9venir les fuites intestinales gr\u00e2ce \u00e0 une meilleure alimentation en oligo-\u00e9l\u00e9ments<\/h3>\n\n\n\n

La paroi du tractus intestinal est constitu\u00e9e de plusieurs couches de tissu \u00e9pith\u00e9lial. Les villosit\u00e9s, ou structures d'absorption de l'intestin, sont tapiss\u00e9es d'ent\u00e9rocytes, o\u00f9 les nutriments sont absorb\u00e9s. Ces cellules sont li\u00e9es les unes aux autres par des structures prot\u00e9iques complexes, dont les \"jonctions serr\u00e9es\". Leur r\u00f4le est d'emp\u00eacher les bact\u00e9ries, les agents pathog\u00e8nes et les toxines de passer entre les ent\u00e9rocytes et dans la circulation sanguine, contribuant ainsi \u00e0 cr\u00e9er une barri\u00e8re physique protectrice.<\/p>\n\n\n\n

Une paroi intestinale saine pr\u00e9sente de longues villosit\u00e9s en forme de doigts qui offrent une grande surface pour la digestion et l'absorption des nutriments. Avant le sevrage, les villosit\u00e9s intestinales (responsables de l'absorption des nutriments) sont fines et allong\u00e9es, alors qu'apr\u00e8s le sevrage, il a \u00e9t\u00e9 d\u00e9montr\u00e9 que la hauteur des villosit\u00e9s diminuait d'environ 75 % au cours des 24 premi\u00e8res heures suivant le sevrage, devenant rapidement \u00e9paisses et courtes. Le raccourcissement des villosit\u00e9s peut nuire \u00e0 la digestion et \u00e0 l'absorption des nutriments. Une r\u00e9duction de l'apport en nutriments compromet \u00e9galement l'int\u00e9grit\u00e9 des jonctions serr\u00e9es.<\/p>\n\n\n\n

Des facteurs tels que le stress thermique, une alimentation r\u00e9duite, des bact\u00e9ries, des contaminants alimentaires, etc., peuvent affaiblir la qualit\u00e9 des jonctions serr\u00e9es, entra\u00eenant un syndrome appel\u00e9 \"intestin perm\u00e9able\" (leaky gut). Cet \u00e9tat - l'intestin perm\u00e9able - permet \u00e0 des mol\u00e9cules telles que les bact\u00e9ries, les agents pathog\u00e8nes et les toxines de passer entre les cellules \u00e9pith\u00e9liales, ce qui entra\u00eene des l\u00e9sions cellulaires et une inflammation de l'intestin. Ce ph\u00e9nom\u00e8ne d\u00e9clenche le syst\u00e8me immunitaire qui a besoin de quantit\u00e9s importantes de nutriments pour faire face \u00e0 l'inflammation, ce qui r\u00e9duit la quantit\u00e9 de nutriments disponibles pour la croissance des porcelets.<\/p>\n\n\n\n

La recherche a d\u00e9montr\u00e9 que l'alimentation d'une g\u00e9n\u00e9ration peut avoir un impact positif ou n\u00e9gatif sur l'alimentation de la g\u00e9n\u00e9ration suivante. Cela est vrai pour les humains comme pour les animaux. Zinpro s'est associ\u00e9 \u00e0 l'Universit\u00e9 de l'Alberta (Caine et al., 2009) pour \u00e9valuer comment l'incorporation d'oligo-\u00e9l\u00e9ments de performance dans l'alimentation de la truie gestante peut aider le porcelet \u00e0 d\u00e9velopper une r\u00e9ponse immunitaire initiale plus robuste.<\/p>\n\n\n\n

Les truies ont \u00e9t\u00e9 divis\u00e9es en deux groupes et ont \u00e9t\u00e9 nourries soit avec des oligo-\u00e9l\u00e9ments inorganiques, soit avec de l'eau. oligo-\u00e9l\u00e9ments de performance<\/a> au cours du dernier stade de la gestation (j 80 \u00e0 114) :<\/p>\n\n\n\n

Traitement inorganique :<\/strong> 120 ppm de Zn provenant de l'oxyde de zinc (ZnO)
Zinpro<\/b>\u00ae<\/b><\/sup> Availa\u00ae<\/sup> Traitement au zinc :<\/strong> 250 ppm de zinc provenant de Zinpro Availa Zinc<\/a> ajout\u00e9 au r\u00e9gime de contr\u00f4le de j 80 \u00e0 j 114 de la gestation.<\/p>\n\n\n\n

Une fois que les truies ont mis bas leur port\u00e9e, elles sont pass\u00e9es \u00e0 un r\u00e9gime de lactation commun et les porcelets ont \u00e9t\u00e9 pr\u00e9lev\u00e9s \u00e0 l'\u00e2ge de 14 jours pour observer leur morphologie intestinale.<\/p>\n\n\n\n

Alors qu'il a \u00e9t\u00e9 d\u00e9montr\u00e9 que la hauteur des villosit\u00e9s diminuait d'environ 75 % au cours des 24 premi\u00e8res heures suivant le sevrage et devenait rapidement \u00e9paisse et courte, les porcelets n\u00e9s de truies recevant du zinc dans Zinpro Availa Zinc pr\u00e9sentaient une hauteur de villosit\u00e9s intestinales plus \u00e9lev\u00e9e et un rapport hauteur des villosit\u00e9s\/profondeur de la crypte plus \u00e9lev\u00e9. Il en r\u00e9sulte une plus grande surface d'absorption des nutriments pour le porcelet, tout en contribuant \u00e0 r\u00e9duire l'incidence de la diarrh\u00e9e.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Une r\u00e9ponse immunitaire plus robuste<\/h3>\n\n\n\n

La morphologie intestinale a \u00e9galement montr\u00e9 une augmentation des lymphocytes intra-\u00e9pith\u00e9liaux qui aident \u00e0 \u00e9liminer les cellules \u00e9pith\u00e9liales intestinales endommag\u00e9es ou infect\u00e9es. Cela contribue \u00e0 am\u00e9liorer la r\u00e9ponse immunitaire intestinale du porc. On a \u00e9galement constat\u00e9 une augmentation des cellules de gobelet dans l'intestin. Les cellules \u00e0 gobelets sont responsables de la production de mucine, et la mucine cr\u00e9e la couche de mucus le long des parois de l'intestin. Les lymphocytes intra-\u00e9pith\u00e9liaux ciblent et d\u00e9truisent les agents pathog\u00e8nes afin de r\u00e9duire la charge pathog\u00e8ne globale. Les cellules \u00e0 gobelet sont responsables de la production de mucine, qui contribue \u00e0 la formation d'une barri\u00e8re muqueuse protectrice pour la paroi de l'intestin.<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

Pour en savoir plus sur les oligo-\u00e9l\u00e9ments de performance et leur r\u00f4le dans la sant\u00e9 intestinale des porcelets, contactez votre repr\u00e9sentant Zinpro<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"

Le taux moyen de mortalit\u00e9 avant sevrage aux \u00c9tats-Unis est d'environ 16 %, avec de fortes variations et des possibilit\u00e9s d'am\u00e9lioration. Il est donc vital pour la survie des porcelets de s'assurer qu'ils d\u00e9veloppent une bonne sant\u00e9 intestinale et une r\u00e9ponse immunitaire initiale robuste en cas de d\u00e9fi. D\u00e9couvrez comment l'administration d'oligo-\u00e9l\u00e9ments aux truies gestantes peut contribuer \u00e0 am\u00e9liorer la sant\u00e9 intestinale et \u00e0 soutenir une r\u00e9ponse immunitaire robuste chez les porcelets.<\/p>","protected":false},"author":74,"featured_media":55848,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_tec_requires_first_save":true,"_eb_attr":"","_uag_custom_page_level_css":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[2682],"tags":[2683,2688,2684,2689,2685,2687],"species":[943],"class_list":["post-56027","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-animal-performance","tag-gut-health","tag-health","tag-heat-stress","tag-immunity","tag-milk-quality"],"acf":[],"yoast_head":"\nSwine Nutrition Impacts Piglet Gut Health and Immune Response – Zinpro\u00ae<\/title>\n<meta name=\"description\" content=\"Blog posts from Zinpro\u00ae about Swine Nutrition Impacts Piglet Gut Health and Immune Response . 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