{"id":56074,"date":"2018-10-04T00:32:31","date_gmt":"2018-10-04T00:32:31","guid":{"rendered":"https:\/\/www.zinpro.com\/performance-trace-minerals-help-with-equine-lameness-and-joint-inflammation-recovery-time\/"},"modified":"2024-02-05T15:29:09","modified_gmt":"2024-02-05T20:29:09","slug":"performance-trace-minerals-help-with-equine-lameness-and-joint-inflammation-recovery-time","status":"publish","type":"post","link":"http:\/\/www.zinpro.com\/pt\/resource-center\/blog\/performance-trace-minerals-help-with-equine-lameness-and-joint-inflammation-recovery-time\/","title":{"rendered":"Performance Trace Minerals ajuda no tempo de recupera\u00e7\u00e3o de claudica\u00e7\u00e3o e inflama\u00e7\u00e3o das articula\u00e7\u00f5es em equinos"},"content":{"rendered":"<p>No mundo dos cavalos de rendimento - corridas, competi\u00e7\u00f5es e exibi\u00e7\u00f5es - muitos dos nossos cavalos jovens e em crescimento passam por um treinamento extenso, e os rigores desse treinamento podem resultar em inflama\u00e7\u00e3o localizada das articula\u00e7\u00f5es, causando desconforto e dor ao cavalo. Al\u00e9m disso, \u00e0 medida que os cavalos envelhecem, independentemente de serem cavalos de desempenho ou de lazer, sabemos que eles podem ser afetados por problemas de inflama\u00e7\u00e3o nas articula\u00e7\u00f5es.<\/p>\n\n\n\n<p>Uma maneira de ajudar a controlar a inflama\u00e7\u00e3o das articula\u00e7\u00f5es dos equinos, que pode levar \u00e0 artrite e \u00e0 claudica\u00e7\u00e3o dos cavalos, \u00e9 a inclus\u00e3o de minerais de desempenho, especialmente zinco (Zn), mangan\u00eas (Mn) e cobre (Cu) na <a href=\"https:\/\/www.zinpro.com\/pt\/species\/equine\/\" target=\"_blank\" rel=\"noreferrer noopener\">nutri\u00e7\u00e3o equina<\/a>. Esses minerais desempenham um papel direto no controle da inflama\u00e7\u00e3o para melhorar o bem-estar do cavalo.<\/p>\n\n\n\n<p>Os lipopolissacar\u00eddeos (LPS) - mol\u00e9culas grandes encontradas na membrana externa de bact\u00e9rias Gram-negativas - podem ser utilizados para estudar uma resposta inflamat\u00f3ria em um modelo de desafio. Quando o LPS \u00e9 injetado na articula\u00e7\u00e3o, ele inicia uma resposta inflamat\u00f3ria que causa a quebra e a renova\u00e7\u00e3o da cartilagem. A Texas A&amp;M University criou um modelo para medir a inflama\u00e7\u00e3o das articula\u00e7\u00f5es de equinos. Zinpro<sup>\u00ae<\/sup> trabalhou com a Texas A&amp;M para pesquisar como a inclus\u00e3o de <a href=\"https:\/\/test-zinpro-wp.pantheonsite.io\/\" target=\"_blank\" rel=\"noopener noreferrer\"> <\/a><a href=\"https:\/\/www.zinpro.com\/pt\/products\/performance-minerals\/\" target=\"_blank\" rel=\"noreferrer noopener\">Minerais de desempenho Zinpro\u00ae.<\/a> na dieta de um cavalo pode produzir uma resposta inflamat\u00f3ria mais robusta e ajudar a articula\u00e7\u00e3o a se recuperar quando ocorre um desafio de LPS.<\/p>\n\n\n\n<p>Os cavalos em crescimento foram classificados em dois grupos:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Grupo 1 - Alimentado com sulfatos de Zn, Cu, Mn e carbonato de Co (INO) por um per\u00edodo de 56 dias<\/li>\n\n\n\n<li>Grupo 2 - Fed 4-Plex<sup>\u00ae<\/sup>C da Zinpro por um per\u00edodo de 56 dias<\/li>\n<\/ul>\n\n\n\n<p>Esses cavalos em crescimento foram ent\u00e3o desafiados com uma inje\u00e7\u00e3o de LPS na articula\u00e7\u00e3o para criar inflama\u00e7\u00e3o e degrada\u00e7\u00e3o da cartilagem no 42\u00ba dia. A outra articula\u00e7\u00e3o do cavalo foi injetada com uma solu\u00e7\u00e3o salina para servir de controle. Amostras de sangue foram coletadas imediatamente antes das inje\u00e7\u00f5es e, em seguida, 6, 12, 24, 168 e 336 horas ap\u00f3s a inje\u00e7\u00e3o para determinar a resposta \u00e0 inflama\u00e7\u00e3o.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-treating-equine-lameness-and-joint-lameness\">Tratamento de claudica\u00e7\u00e3o equina e claudica\u00e7\u00e3o articular<\/h3>\n\n\n\n<p>Dentro de seis horas ap\u00f3s a inje\u00e7\u00e3o, os cavalos de ambos os grupos apresentaram um aumento significativo da prostaglandina pr\u00f3-inflamat\u00f3ria (PGE<sub>2<\/sub>). Isso significa que o sistema imunol\u00f3gico est\u00e1 respondendo ao desafio do LPS.<\/p>\n\n\n\n<p>O que \u00e9 interessante notar \u00e9 que a PGE<sub>2<\/sub> A resposta foi substancialmente maior nos cavalos alimentados com <a href=\"https:\/\/www.zinpro.com\/pt\/products\/original-line\/4-plex-c\/\" target=\"_blank\" rel=\"noreferrer noopener\">4-Plex C<\/a> do Zinpro, resultando em um pico de resposta mais r\u00e1pido ao desafio de LPS. Em 24 horas, a PGE<sub>2<\/sub> diminui, como deveria, mas os cavalos alimentados com o 4-Plex-C ainda t\u00eam um n\u00edvel mais alto de EGP<sub>2<\/sub> resposta.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img decoding=\"async\" src=\"http:\/\/www.zinpro.com\/wp-content\/uploads\/2023\/06\/Chart-1024x283-1.jpg\" alt=\"\" class=\"wp-image-15285\"\/><\/figure>\n\n\n\n<p>O estudo tamb\u00e9m descobriu que os n\u00edveis de C2C (neopept\u00eddeo de clivagem de colagenase catab\u00f3lica) - um marcador do metabolismo do col\u00e1geno que fornece uma medida do col\u00e1geno tipo II na cartilagem da articula\u00e7\u00e3o - eram maiores seis horas ap\u00f3s a inje\u00e7\u00e3o. A degrada\u00e7\u00e3o da cartilagem pode ser considerada como um \"processo de limpeza\" - o tecido da articula\u00e7\u00e3o precisava ser degradado antes de ser virado e substitu\u00eddo. A C2C \u00e9 um indicador das prote\u00ednas que trabalham para limpar a cartilagem danificada ap\u00f3s a presen\u00e7a da bact\u00e9ria LPS. Isso \u00e9 importante porque nos diz que houve uma resposta de \"limpeza\" mais r\u00e1pida e mais robusta da cartilagem articular nos cavalos alimentados com o 4-Plex-C da Zinpro.<\/p>\n\n\n\n<p>As mol\u00e9culas de aggrecan, que proporcionam resist\u00eancia \u00e0 compress\u00e3o da articula\u00e7\u00e3o, s\u00e3o medidas pelo marcador de ep\u00edtopo CS-864, que fornece uma medida da s\u00edntese da mol\u00e9cula de aggrecan. Os cavalos alimentados com o 4-Plex-C da Zinpro n\u00e3o apenas apresentaram o pico mais precoce no marcador de ep\u00edtopo CS-864 em 12 horas, mas tamb\u00e9m o mais alto, com 249.000 ng\/mL, em compara\u00e7\u00e3o com 150.000 ng\/mL entre os cavalos alimentados com o tra\u00e7o mineral INO. Isso \u00e9 importante porque indica que a s\u00edntese da mol\u00e9cula de aggrecan est\u00e1 ocorrendo muito mais rapidamente quando os cavalos s\u00e3o alimentados com 4-Plex-C da Zinpro. Isso \u00e9 positivo para o restabelecimento do tecido funcional na articula\u00e7\u00e3o ap\u00f3s o in\u00edcio da inflama\u00e7\u00e3o.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-4-plex-c-from-zinpro-helps-manage-joint-inflammation-in-horses\">4-Plex C da Zinpro ajuda a controlar a inflama\u00e7\u00e3o das articula\u00e7\u00f5es em cavalos<\/h3>\n\n\n\n<p>A inclus\u00e3o do 4-Plex-C na dieta de um cavalo mostra que, quando h\u00e1 inflama\u00e7\u00e3o na articula\u00e7\u00e3o do equino, h\u00e1 uma resposta imunol\u00f3gica mais r\u00e1pida \u00e0 inflama\u00e7\u00e3o, uma \"limpeza\" mais r\u00e1pida e robusta do tecido da cartilagem e uma reconstru\u00e7\u00e3o muito mais r\u00e1pida das prote\u00ednas na cartilagem da articula\u00e7\u00e3o.<\/p>\n\n\n\n<p>Isso n\u00e3o significa que a inclus\u00e3o de minerais de desempenho na dieta evitar\u00e1 toda a inflama\u00e7\u00e3o das articula\u00e7\u00f5es. Significa apenas que, ao alimentar o 4-Plex-C da Zinpro, o cavalo ter\u00e1 uma resposta mais robusta a um desafio de LPS, resultando em um animal mais resistente que sair\u00e1 do desafio de LPS mais cedo e preparando o cavalo para o sucesso.<\/p>\n\n\n\n<p>Entre em contato com o seu <a href=\"https:\/\/www.zinpro.com\/pt\/products\/original-line\/4-plex-c\/\" target=\"_blank\" rel=\"noreferrer noopener\">Representante da Zinpro<\/a> para saber como os minerais tra\u00e7o de desempenho, como o&nbsp;<a href=\"https:\/\/www.zinpro.com\/pt\/products\/original-line\/4-plex-c\/\" target=\"_blank\" rel=\"noreferrer noopener\">4-Plex C<\/a> ou <a href=\"https:\/\/www.zinpro.com\/pt\/products\/availa-mins\/availa-4\/\" target=\"_blank\" rel=\"noreferrer noopener\">Availa\u00ae 4<\/a>O produto, que melhora a nutri\u00e7\u00e3o dos equinos e promove uma melhor resposta imunol\u00f3gica.<\/p>\n\n\n\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>A inflama\u00e7\u00e3o das articula\u00e7\u00f5es \u00e9 um problema significativo em cavalos de desempenho, afetando seu bem-estar geral. A inclus\u00e3o de minerais tra\u00e7o em seu plano de alimenta\u00e7\u00e3o de nutri\u00e7\u00e3o equina pode ajudar a limitar a claudica\u00e7\u00e3o dos cavalos e promover uma recupera\u00e7\u00e3o mais r\u00e1pida.<\/p>","protected":false},"author":31,"featured_media":55863,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_tec_requires_first_save":true,"_eb_attr":"","_uag_custom_page_level_css":"","_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"_tribe_blocks_recurrence_rules":"","_tribe_blocks_recurrence_description":"","_tribe_blocks_recurrence_exclusions":"","_ecp_custom_2":"","footnotes":""},"categories":[2682],"tags":[2686,2695,2690],"species":[],"class_list":["post-56074","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","tag-inflammation","tag-joint-function","tag-lameness"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.4 (Yoast SEO v27.4) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Performance Trace Minerals Help with Equine Lameness and Joint Inflammation Recovery Time &#8211; Zinpro\u00ae<\/title>\n<meta name=\"description\" content=\"Blog posts from Zinpro\u00ae about Performance Trace Minerals Help with Equine Lameness and Joint Inflammation Recovery Time . 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